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. 2020 May 26;11(5):e00178. doi: 10.14309/ctg.0000000000000178

Figure 4.

Figure 4.

Overexpression of xCT (SLC7A11) gene could reduce the GES-1 apoptosis induced by H. pylori. (a) The expression of GFP was obviously induced in plasmid transgenic cell lines. (b) Western blot for xCT in GES-1. (c) LDH was assessed for cell damage. (d) Caspase-3 activity. Data are means ± SEM, N = 4, *P < 0.05 vs control, **P < 0.01 vs control. ##P < 0.01 vs H. pylori SS1. GES-1, gastric mucosa epithelial; Hp, Helicobacter pylori; LDH, lactic dehydrogenase; SS1, Sydney strain 1; xCT, cystine-glutamate transporter.