Figure 3.

High Laidx sequence identity between mouse and Chinese liver fluke suggests a horizontal gene transfer event. (A) Blastp alignment of the 5280 amino acid Clonorchis protein CSKR_14446s and the predicted 8337 amino acid LAIDX protein. (B) TBLASTN alignment of Laidx with Clonorchis genomic sequence encoding CSKR_14446s. (C) Evolutionary history of Laidx. Species that carry a Laidx ortholog are marked with a “+”. An orange arrow and orange branches mark a proposed horizontal gene transfer event that occurred between a mouse/rat ancestor and the liver fluke. Mya, Million years ago.