Table 2.

HSA structural quantities

Quantity	Description	Units
Nnbr	Average # first shell neighbors	None
NwwHB	Average # water-water hydrogen bonds	None
NswHB	# solute-water hydrogen bonds	kcal/mol
EnbrWW	Average water-water interaction energy by neighbor	Kcal/nbr
NwwHB,don	# water-water hydrogen bonds donated	None
NwwHB,acc	# water-water hydrogen bonds accepted	None
NswHB,don	# solute-water hydrogen bonds donated	None
NswHB,acc	# solute-water hydrogen bonds accepted	None
fwwHB	Fraction of hydrogen-bonded neighbors	None