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. 2020 May 26;13:4731–4742. doi: 10.2147/OTT.S251916

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© 2020 Wu et al.

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Overexpression of miR-877-5p suppresses proliferation of gastric cancer (GC) cells in vivo, in a mouse model. (A) Individual xenograft tumors were sampled from miR-877-5p over-expressing group and the counterparts. (B) A tumor growth curve was drawn based on the tumor volume measurement every 4 d. (C) Comparison of the tumor weights which was presenting as average±SD in two groups. (D) Expression levels of miR-877-5p in the xenograft tumors from the two groups averaging from each individual. (E, F) Expression levels of tumor mRNA and protein of FOXM1 from the two groups, respectively. Both mRNA and protein level of FOXM1 was dropped when miR-877-5p was over-expressed. ***P < 0.005.