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In-vitro pharmacokinetic parameters of bictegravir (BIC) as NP and solution.
| PK Parameter/106 cells | Unit | BIC NP | BIC Solution |
|---|---|---|---|
| Cmax | pmole | 888.54 ± 226.73 | 372.3 ± 137.54 |
| AUCall | h × pmole | 31,654.77 ± 4186.15 | 10,053.24 ± 1187.96 |
| Clearance | pmole/(h × pmole) | 0.010 | 0.044 |
Data represents mean ± standard error of means (SE), n = 3; AUCall = area under the plasma concentration-time curve (from 0-end of experiment).
