Table 3.

In vitro safety and efficacy comparison of BIC NP versus BIC solution.

Cell type	Treatment Type	Cytotoxicity (CC50 (μM))	HIV inhibition (EC50 (μM))	Selectivity (SI)
TZM-bl	BIC NP	820.4 ± 2.27	0.0038 ± 0.0023	215,789
cell	BIC	2.25 ± 1.46	0.604 ± 0.593	3.7
line	solution
PBMCs	BIC NP	15.7 ± 1.33	0.076 ± 0.45	523.33
	BIC	3.4 ± 1.26	2.33 ± 2.15	1.5
	solution

The data represents means ± SE of three independent experiments or donors analyzed in triplicate, respectively. SI = CC₅₀/IC₅₀.