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. 2020 May 26;13:4665–4678. doi: 10.2147/OTT.S245681

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© 2020 Yang et al.

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Apoptosis-related proteins detected among the different groups of ECA109 and KYSE30 cells in vitro. (A) Significant downregulation of Bid and Mcl-1 and upregulation of caspase-3 were observed in FAM83D-depletion ECA109 and KYSE30 cells compared to control cells before exposure to radiation. (B) Similar results were observed after exposure to radiation. In addition, the expression levels of the above indexes after irradiation in the three groups were higher than those before IR. **P<0.01 compared with the control and NC groups; ^▲▲P<0.01 compared with the corresponding unirradiated group.