Table 1.
Correlation Between FAM83D Expression and Clinicopathological Variables in Patients with ESCC
| Variables | Patients | FAM83D Expression | P-value | |
|---|---|---|---|---|
| Negative | Positive | |||
| Sex | ||||
| Male | 35 | 17 | 18 | 0.537 |
| Female | 34 | 14 | 20 | |
| Age, years | ||||
| ≤55 | 35 | 15 | 20 | 0.726 |
| >55 | 34 | 16 | 18 | |
| Tumor size | ||||
| ≤5 cm | 34 | 11 | 23 | 0.029 |
| >5 cm | 35 | 20 | 15 | |
| Lesion location | ||||
| Neck/upper | 37 | 16 | 21 | 0.762 |
| Middle/lower | 32 | 15 | 17 | |
| TNM stage | ||||
| I–II | 32 | 10 | 22 | 0.034 |
| III–IV | 37 | 21 | 16 | |
| T classification | ||||
| T1-T2 | 30 | 9 | 21 | 0.020 |
| T3-T4 | 39 | 22 | 17 | |
| N classification | ||||
| N0 | 29 | 9 | 20 | 0.048 |
| N1-N3 | 40 | 22 | 18 | |
| Distant metastasis | ||||
| M0 | 28 | 8 | 20 | 0.024 |
| M1 | 41 | 23 | 18 | |
| Relapse | ||||
| Negative | 27 | 7 | 20 | 0.011 |
| Positive | 42 | 24 | 18 | |
Notes: All cases were classified into clinical TNM stage according to the criteria of the UICC and the AJCC in 2009.
Abbreviations: UICC, International Union against Cancer; AJCC, American Joint Committee on Cancer; TNM, tumor-node-metastasis.