Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 May 26;12:3915–3925. doi: 10.2147/CMAR.S240719

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Wang et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

The circMTO1/miR-9-5p/NOX4 axis regulated the proliferation and apoptosis in hepatoma cells. (A, C) NOX4 mRNA levels in HepG2 and Hep3B cells transfected with pcDNA-circMTO1, pcDNA-NOX4 and miR-9-5p mimic. (B, D) Proliferation rate of cells transfected with the different constructs. (E) In vitro migration rate of cells transfected with the different constructs. (F) Apoptosis rate in the cells transfected with different constructs. * P<0.05, **P<0.01, ***P<0.001 compared with NC, ^#P<0.05, ^##p<0.01, ^###p<0.001 compared with miR-9-5p mimic, ^&P<0.05, ^&&P<0.01, ^&&&P<0.001 compared with pcDNA-circMTO1, ^δP<0.05, ^δδP<0.01 compared with pcDNA-NOX4.

Abbreviations: NC, negative control; FITC, fluorescein isothiocyanate; PI, propidium iodide; FL1-H, fluorescent channel 1; FL2-H, fluorescent channel 2.