Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 May 26;12:3927–3936. doi: 10.2147/CMAR.S244317

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 Bai and Li.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

hsa_circ_0008285 regulated SOX4 expression via miR-211-5p. (A) miR-211-5p inhibitors abolished the effects of silencing of hsa_circ_0008285 on SOX4 protein expression in Hela and C33A cells. (B, C) The SOX4 expression in CC tissues and cell lines was measured by qRT-PCR. (D) SOX4 expression in CC tissues was measured by IHC. (E) SOX4 inhibition significantly reduced CC cells invasion ability. (F, G) High SOX4 expression was associated with poor OS and DFS in CC patients. (H) hsa_circ_0008285 expression was positively correlated with SOX4 expression in CC patients. *P<0.05.