Table 2. Body weight and food intake in high cholesterol diet fed LDL receptor knockout mice for 10 weeks.
Group1) | Initial body weight (g) | Final body weight (g) | Body weight gain (g) | Food intake (g/day) | Food efficiency ratio (%)2) |
---|---|---|---|---|---|
Control | 19.20 ± 1.23NS | 23.61 ± 1.64NS | 4.41 ± 1.01NS | 2.32 ± 0.41NS | 21.11 ± 4.84NS |
CS50 | 18.98 ± 1.39 | 23.86 ± 1.75 | 4.89 ± 1.19 | 2.36 ± 0.40 | 23.00 ± 5.58 |
CS100 | 18.68 ± 1.33 | 23.54 ± 1.69 | 4.86 ± 0.78 | 2.30 ± 0.39 | 23.47 ± 3.76 |
SCS100 | 18.79 ± 1.53 | 23.20 ± 1.53 | 4.41 ± 0.83 | 2.27 ± 0.42 | 23.32 ± 4.40 |
SCS200 | 18.80 ± 1.69 | 23.51 ± 1.63 | 4.71 ± 0.78 | 2.38 ± 0.41 | 22.03 ± 3.66 |
Values are mean ± SD (n = 8 each group). Statistical analyses were conducted by Duncan's multiple range test (P < 0.05). NS, Non-significance.
1)Control, LDL receptor knockout (LDLR-KO) mice fed high cholesterol diet (HCD) and oral administration (OA) of purified water; CS50 and CS100, LDLR-KO mice fed HCD and OA of CS at a concentration of 50 and 100 mg/kg/day, respectively; SCS100 and SCS200, LDLR-KO mice fed HCD and OA of SCS at a concentration of 100 and 200 mg/kg/day, respectively.
2)Food efficiency ratio (%) : (total weight gain/total food intake) × 100.