Fig. 1. Effects of L-histidine, L-carnosine, and their combination on proliferation.

The neuronal proliferation was assessed by MTT assay. (A) L-histidine and (B) L-carnosine were treated with various concentrations for 48 h. (C) His, Car, and His+Car were treated for 48 h and assessed by MTT assay. The values shown are the mean ± standard error of the mean (n = 3–4).

Ctrl, Control; D-gal, 200 mM D-galactose; His, 1 mM L-histidine; Car, 10 mM L-carnosine; His+Car, 1 mM L-histidine + 10 mM L-carnosine.

^*,†,‡,§Different superscript marks indicate significant differences between groups (P < 0.05).