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NOSH-aspirin mediated cell growth inhibition is reversed by zVAD. MIA PaCa-2 and BxPC-3 cells, pretreated with 2 μM z-VAD-FMK for 4 hr or untreated, were followed by 50 nM NOSH-aspirin (~IC50 concentration) and subsequently analyzed for growth as described in Section 2.2. Values represent means ± SEM of three representative experiments performed in triplicate. *P < 0.05 compared to absence of z-VAD.
