Table 3.
[11C]-(+)-PHNO dose-occupancy results.
| Region-based | ICA | |||
|---|---|---|---|---|
| D2 | D3 | IC1 | IC2 | |
| EC50 (S.E.), μg/mL | 48 (8.5) | 5.6 (2.6) | 48 (9.0) | 6.7 (2.0) |
| Maximum occupancy, % | fixed to 100 | 89 (S.E. 9.0) | fixed to 100 | ~100 |
| RMSE | 5.0 | 6.1 | 5.3 | 4.2 |
RMSE, root mean square error.