Table 1.
Timeline of outcome assessments
| Outcome Measures | Baseline | 10 Weeks | 6 Months | 2 Years |
|---|---|---|---|---|
| Motion Analysis: Peak Knee Extension Moment | X | X | X* | X |
| Physical Function: SCT, 30-STS, 6MW, TUG, Physical Activity | X | X | X | X |
| Self-Report Measures: WOMAC, VR-12 | X | X | X | X |
| Quadriceps Muscle Strength: Dynamometry | X | X | X | X |
| Knee Range of Motion: Goniometry | X | X | X | X |
| Satisfaction | X | |||
| Adherence | X | |||
| Knee OA progression: MRI (WORMS score) | X | X | ||
| Incidence of contralateral TKA | X |
Note: SCT, stair climb test; 30-STS, 30 second sit-to-stand test; 6MW, six minute walk test; TUG, timed up and go test; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index survey; VR-12, Veterans Rand 12-item health survey; MRI, magnetic resonance imaging; OA, osteoarthritis; WORMS, Whole-Organ Magnetic Resonance Imaging Score.
*
indicate primary outcome and time point.