Table 2.
Median dose in cGy (range) to PTV for C3D, C3D FFF, IMRT, and VMAT plans.
| PTV | C3D | C3D FFF | IMRT | VMAT | Friedman | |
|---|---|---|---|---|---|---|
| Maximuma | 5784 (5602−5952) | 5842 (5633−6046) | 5725 (5613−5841) | 5835 (5765−5946) | <0.0001 | |
| Minimuma | 5145 (4312−5302) | 5134 (4575−5293) | 5111 (4282−5252) | 5033 (4420−5227) | <0.0001 | |
| Meana | 5612 (5502−5729) | 5633 (5512−5755) | 5556 (5513−5629) | 5565 (5456−5633) | <0.001 | |
| D95% | cGy | 5400 (5318−5494) | 5400 (5319−5488) | 5400 (5381−5430) | 5400 (5121−5429) | 0.958 |
| % | 100 (98.5−101.7) | 100 (98.5−101.6) | 100 (99.7−100.6) | 100 (94.8−100.5) | 0.985 | |
| D98% | cGy | 5340 (5213−5414) | 5338 (5203−5410) | 5346 (5302−5380) | 5341 (5038−5359) | <0.0001 |
| % | 98.9 (96.5−100.3) | 98.9 (96.4–100.2) | 99 (98.2−99.6) | 98.9 (93.3−99.2) | 0.001 | |
| D50% | cGy | 5633 (5507−5777) | 5653 (5517–5786) | 5576 (5519−5667) | 5577 (5492−5673) | <0.0001 |
| % | 104.3 (102−107) | 104.7 (102.2–107.1) | 103.3 (102.2−105) | 103.3 (101.7−105.1) | <0.0001 | |
| D2% | cGy | 5765 (5591−5963) | 5813 (5616–6012) | 5666 (5593–5747) | 5728 (5646–5863) | <0.0001 |
| % | 106.8 (103.5−109.9) | 107.6 (104−111.3) | 104.9 (103.6−106.4) | 106.1 (104.6–108.6) | <0.0001 | |
| V95% | 99.91 (99.46−100) | 100 (99.38−100) | 100 (99.5−100) | 99.98 (94.64−100) | 0.011 | |
| V107% | 0.27 (0−49.66) | 10.07 (0−51.81) | 0 (0−0.35) | 0.23 (0−14.56) | <0.0001 | |
| HI1 | 1.07 (1.04−1.10) | 1.08 (1.04−1.12) | 1.06 (1.04−1.08) | 1.08 (1.07−1.10) | <0.0001 | |
| HI2 | 0.08 (0.04−0.12) | 0.09 (0.05−0.13) | 0.06 (0.04−0.08) | 0.07 (0.05−0.14) | <0.0001 | |
| CI1 | 1.56 (1.13−2.15) | 1.52 (1.14−2.1) | 1.06 (0.95−1.34) | 1.01 (0.25−1.12) | <0.0001 | |
| CI2 | 0.41 (0.29−0.53) | 0.42 (0−0.56) | 0.64 (0−0.77) | 0.74 (0.59−0.82) | <0.0001 | |
D95%, D98%, D50% and D2%: dose received by 95%, 98%, 50% and 2% of PTV in cGy or percentage. V95% and V107%: volume of PTV receiving or within the 95% and 107% isodose.
HI1: homogeneity index calculated as maximum dose divided by prescribed dose.
HI2: homogeneity index calculated as (D2%–D98%)/prescribed dose.
CI1: conformity index calculated as treatment volume divided by PTV volume (VPTV).
CI2: conformity index calculated as (V95% ∩ VPTV)2/(V95% * VPTV).
Abbreviations: PTV, planning target volume; C3D, conformal 3D radiotherapy; C3D FFF, conformal 3D radiotherapy flattening filter-free; IMRT, modulated intensity radiotherapy; VMAT, volumetric modulated arc therapy; HI homogeneity index; CI, conformity index.
Median dose (range) in cGy.