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. 2020 May 26;11:767. doi: 10.3389/fphar.2020.00767

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Copyright © 2020 Jiang, Wang, Luo, Lin, Feng, Yan, Shi, Zhang, Gu, Cui, Wang, Wang, Zhang and Tan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Polyporus polysaccharide (PPS) inhibits transforming growth factor β1 (TGF-β1)–induced human lung fibroblasts (HLFs) proliferation and migration. (A) Cell viability after different treatments was detected using a CCK-8 Kit. (B) Representative image is the scratch assay was used to measure fibroblast migration after TGF-β1 treated 24 and 48 h, respectively (Scale bars, 50 μm). (C) Scatter plots show the mean ± SD quantitative results obtained from three independent scratch assays on 3 different days. ^# = p < 0.05, ^## = p < 0.01 versus Con; * = p < 0.05, ** = p < 0.01 versus TGF-β1 treated alone.