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. 2020 Jun 1;10:8830. doi: 10.1038/s41598-020-63757-3

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Receiver operating characteristics showing the average predictive performance for Rheumatoid Arthritis. The specificity and sensitivity rate for 5 genes showing the Area Under the Curve (AUC) for patients presenting to the clinic with a diagnosis of RA at Day 0, 6 Months and 12 months follow-up, when compared to healthy individuals. Receiver operating characteristic curves of (A) SIGLEC1, (B) MSA4A, (C) PDZK1IP1, (D) EPHB2 and (E) ST6GALNAC1 are presented.