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. 2020 Jun 1;11(6):409. doi: 10.1038/s41419-020-2606-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Schematic diagram for the development eosinophilic airway inflammation in mice and therapy interventions of MSC-sEV. b Representative figures and statistical results of H&E and PAS staining for lung tissues. c–e Cell counts for inflammatory cells by flow cytometry in BALF. f Levels of Th2-related cytokines in the BALF. **P < 0.01, ***P < 0.001, ****P < 0.0001. Alum Aluminum, BALF bronchoalveolar lavage fluids, EVs Extracellular Vesicles, H&E Hematoxylin–Eosin, i.p. intraperitoneally, MSC Mesenchymal stromal cells, ns not significant, OVA ovalbumin, PAS periodic acid-schiff, PBS phosphate buffer saline. N = 5 for PBS/PBS/PBS, OVA/OVA/PBS and OVA/OVA/MSC-EVs. Scale bar, 150 µm.