Table 1.

Trastuzumab IC-50 values of Parental and Trastuzumab-resistant SKBR3 cells in the presence and absence of Propofol.

Condition	IC-50
Parental SKBR3	8.7 ± 0.6
Parental SKBR3 + Propofol	4.6 ± 0.4
Tr-R SKBR3	>20
Tr-R SKBR3 + Propofol	5.1 ± 0.4

Experiment described in Fig. 1 was used to calculate all the IC-50 values. Treatment was for a total of 96 hours. Propofol concentration was 5 μg/ml. Control cells (without propofol) were treated with equal volume of DMSO vehicle. All IC-50 values are in the units of μg/ml. Tr-R SKBR3: Trastuzumab resistant SKBR3 cells. >20: IC-50 could not be achieved at the highest concentration of 20 μg/ml Trastuzumab tested.