Table 1.
Anthropometric characteristics and exercise test variables in healthy controls and patients with and without metabolic myopathies.
| Control | Non-metabolic Myalgia | MAD Absent | McArdle | Respiratory Chain Deficiency | |
|---|---|---|---|---|---|
| Anthropometric data | |||||
| Number (n) | 35 | 60 | 10 | 9 | 4 |
| Sex (f/m) | 17/18 | 20/40 | 4/6 | 5/4 | 1/3 |
| Age (years) | 40.1 ± 12.9 | 42.5 ± 13.6 | 39.9 ± 15.6 | 43.3 ± 25.9 | 40.5 ± 16.4 |
| BMI (kg.m−2) | 23.9 ± 4.9 | 24.3 ± 4.5 | 27.1 ± 7.0 | 22.5 ± 3.5 | 24.0 ± 4.9 |
| Isometric handgrip test | |||||
| MVC (DaN) | 39.7 ± 8.8 | 38.2 ± 12.1 | 37.4 ± 10.8 | 26.7 ± 7.9 * | 33.9 ± 14.1 |
| %Pred. MVC | 97.1 ± 12.4 | 87.6 ± 18.9† | 87.9 ± 19.9 | 78.5 ± 9.3† | 76.1 ± 30.2 |
| Progressive cycle ergometer test | |||||
| Maximal power (W) | 195.3 ± 64.5 | 183.4 ± 64.6 | 134.0 ± 59.7 | 68.1 ± 19.6†‡§ | 128.5 ± 69.5 |
| % Pred. maximal power | 107.3 ± 20.9 | 98.2 ± 21.9 | 71.7 ± 17.1 *# | 43.8 ± 14.6 *# | 67.5 ± 30.7 * |
| Peak V’O2 (ml.min−1.kg−1) | 34.3 ± 8.2 | 32.6 ± 9.2 | 28.7 ± 12.9 | 21.2 ± 7.0 *# | 27.3 ± 11.4 |
| % Pred. peak V’O2 | 106.8 ± 21.4 | 100.8 ± 18.0 | 89.6 ± 20.3 | 66.9 ± 11.1 *# | 78.7 ± 26.9 |
| Ratio MVC/MP | |||||
| %Pred. MVC / %Pred. maximal power | 0.92 ± 0.13 | 0.92 ± 0.25 | 1.29 ± 0.43 | 1.96 ± 0.66 †‡ | 1.24 ± 0.42 |
Data are reported as mean ± SD. MAD, Myoadenylate deaminase; BMI, Body Mass Index; MVC, maximal voluntary contraction force; Peak V’O2, maximum oxygen consumption; MP, Maximal Power. Data were analyzed by a one-way ANOVA, followed by post-hoc Scheffé’s or Games-Howell pairwise comparison tests according to Levene’s test results for homogeneity of variance. *significantly different from Control (p < 0.05, Post hoc Scheffe’s multiple comparison test). #significantly different from non-metabolic myalgia (p < 0.05, Post hoc Scheffe’s multiple comparison test). †significantly different from control (p < 0.03, Games-Howell post hoc test). ‡significantly different from non-metabolic myalgia (p < 0.03, Games-Howell post hoc test). §significantly different from respiratory chain deficiency (p < 0.05, Games-Howell post hoc test).