Fig. 1. Expression of Treg-associated genes along Treg differentiation in the thymus.

a Schematic representation of the developmental paths of Treg cells. DN: double negative T cells, DP: double positive T cells, imCD4SP: immature CD4 single positive T cells, Prec: Treg precursor cells, tTreg: thymic Treg cells, Tconv: conventional T cells. b The gene expression profile of the Treg-associated genes based on the deposited RNA-seq data.²⁶ Relative expression level of each gene at each developmental stage is shown.