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. 2020 May 4;30(6):465–474. doi: 10.1038/s41422-020-0324-7

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© Center for Excellence in Molecular Cell Science, CAS 2020

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Fig. 3 — a Developmental events in the genome along tTreg differentiation. Satb1: Satb1 expression, Histone modif: Treg-type histone modifications, SE: Treg-specific super-enhancers, DNAdemethyl: Treg-specific DNA demethylation, FoxP3 exp: FoxP3 expression. b Developmental changes in Satb1-binding and H3K27ac modification. The super-enhancer region at the Foxp3 gene locus is indicated by bar.