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. 2020 Jun 1;11:2719. doi: 10.1038/s41467-020-16322-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Phylogenetic tree and linked epidemiological and genotypic data of 24 retrospective ST340 genomes. Origin type defined as either community-acquired infection (CAI) or hospital-acquired infection (HAI). NA ward information not available. The imipenem (IPM) phenotype was either resistant (R) or susceptible (S). The three-letter antibiotic codes in the resistance profiles are as in Table 1. This interactive view is available at https://microreact.org/project/ARSP_KPN_ST340_2013-14/ac2a0920. The maximum-likelihood tree was inferred from 196 SNP positions identified by mapping the genomes to reference CAV1217 (CP018676.1 [https://www.ncbi.nlm.nih.gov/nuccore/CP018676.1]), and masking regions corresponding to mobile genetic elements and recombination. The scale bar shows the number of SNPs per variable site. The full data are available at https://microreact.org/project/ARSP_KPN_ST340_2013-14. b Distribution of 33 isolates from hospital MMH with resistance profile RP-6 by patient age group, sequence types (ST) and NDM plasmid. Short reads of the 33 isolates were mapped to the plasmid sequences and a match was counted when the reads covered at least 95% of the sequence length with at least 5× depth of coverage. ND not detected.