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. 2020 Jun 1;10:8845. doi: 10.1038/s41598-020-64083-4

Figure 13.

Figure 13

In-degree distribution for several choices of k: The distributions are realized by merging the degree distributions of 1000 different realizations of O(100)-node graphs. For low values of k (i.e. k=5) we see that, for both the H and AF cases, the majority of nodes display rather low in-degree, and the in-degree distribution exhibits a long tail. Conversely, for the CD case, the in-degree is rather homogeneous up to din10, beyond which the tendency of nodes to acquire more links is softened (apart for a tiny fraction of nodes with din20÷25). By increasing k, nodes with low degree get fewer but still the most predominant for both H and AF patients but new peaks appear in the distribution (see k=10) highlighting a change of the topological structure of the network (see also the CD case). This structural change is clear for higher values of k (i.e. k=20), especially for H and CD, for which low-linked nodes are fewer, the majority of nodes presenting an in-degree comparable with k (din20÷25), ultimately suggesting that the networks are becoming regular.