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. 2020 May 26;11:511. doi: 10.3389/fgene.2020.00511

TABLE 2.

Comparison of MICA alleles to driver gene mutations in CRC.

Allele Driver mutation n = 50 (%) KRAS codon 12 n = 29 (%) No mutation n = 52 (%)
*002:01 15 (30.00) 10 (34.48) 10 (19.23)
*004 1 (2.00) 0 (00.00) 2 (3.85)
*007:01 4 (8.00) 1 (3.45) 1 (1.92)
*008 16 (32.00) 9 (31.03) 17 (32.69)
*009:01 or *049 6 (12.00) 4 (13.79) 3 (5.77)
*010:01 15 (30.00) 8 (27.59) 24 (46.15)
*012:01 12 (24.00) 10 (34.48)a 7 (13.46)
*017 0 (0.00) 0 (0.00) 2 (3.85)
*019 10 (20.00) 6 (20.69) 6 (11.54)
*027 2 (4.00) 2 (6.89) 5 (9.62)
*045 1 (2.00) 1 (3.45) 5 (9.62)

ap = 0.027 KRAS codon 12 mutation vs. no mutation in CRC, Mantel-Haenszel stratification test χ2 = 4.90, OR = 3.33 (1.09–10.58). Bold values show the statistical significance.