Figure 1.

LINC01234 Is Highly Expressed in NSCLC and Correlated with Poor Prognosis

(A and B) Data mining of altered lncRNA expression in (A) TCGA dataset (LUAD and LUSC) and (B) two microarray gene profiles (GEO: GSE31210 and GSE18842). (C) Venn diagrams showing lncRNAs commonly upregulated and downregulated in all three datasets. (D) Data mining of the fold change of LINC01234 in TCGA and microarray datasets. (E) In situ hybridization shows the expression of LINC01234 in NSCLC tissues and adjacent nontumor tissues. (F) qRT-PCR analysis of LINC01234 expression in 95 pairs of NSCLC tissues and adjacent nontumor lung tissues, 16HBE cells, and NSCLC cell lines. (G) Kaplan–Meier survival analysis of the association between LINC01234 expression level and NSCLC patient overall survival and disease-free survival. ∗p < 0.05, ∗∗p < 0.01.