Figure 1.

Genome organization of SARS‐CoV‐2, highlighting open reading frames (ORF 1a and ORF 1b) nonstructural, structural and accessory proteins along with both proteases and their corresponding cleavage sites. The 16 nsps are numbered and are shown shaded in gray with the exceptions of PLpro (blue) and 3CLpro (red). The structural and accessory proteins are shown and individual ribbon diagrams for each protease are also shown in individually colored boxes PLpro (blue dashed box) and 3CLpro (red dashed box). The PDB codes for 3CLpro and PLpro from SARS‐CoV‐2 (COVID‐19) are also shown.