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. 2020 May 26;11:1068. doi: 10.3389/fmicb.2020.01068

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Copyright © 2020 Tahrioui, Ortiz, Azuama, Bouffartigues, Benalia, Tortuel, Maillot, Chemat, Kritsanida, Feuilloley, Orange, Michel, Lesouhaitier, Cornelis, Grougnet, Boutefnouchet and Chevalier.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of GA-enriched fractions from PLFE1 on Pseudomonas aeruginosa virulence. (A) Pyocyanin production upon exposure to different concentrations of GA-enriched fractions. (B) Anti-virulence of GA-enriched in human A549 lung cells infection model. The presence of GA-enriched fractions (100 μg mL^–1) significantly protected A549 lung cells from lysis after 20 h infection. Data are presented as the mean ± SEM values of four independent experiments performed in duplicate. Statistics were achieved by a two-tailed t test: ****, P < 0.0001; ***, P = 0.0001 to 0.001; **, P = 0.001 to 0.01; *, P = 0.01 to 0.05; ^{NS (NotSignificant)}, P ≥ 0.05.