TABLE 2.
Initial hemodynamic and laboratory values among hospitalized patients with COVID-19
| All (n = 68) | Moderate disease (n = 41) | Severe disease (n = 27) | P-value | |
|---|---|---|---|---|
| Vitals, median (IQR) | ||||
| Maximum temperature (°C) | 37.4 (37.1-37.9) | 37.6 (37.1-38.1) | 37.2 (36.7-37.4) | .03 |
| Heart rate (per min) | 93.5 (83-104) | 93 (85-106) | 94 (80-101) | .52 |
| Respiratory rate (per min) | 20 (18-24) | 19 (18-21) | 22 (19-39.5) | .01 |
| Lowest O2 sat (%) | 94 (91-96) | 95 (92-96) | 91 (88-94) | .01 |
| Blood counts, median (IQR) | ||||
| WBC × 1000/μL | 5.16 (3.5-7.5) | 5.66 (3.67-7.4) | 4.4 (2.5-10.43) | .63 |
| Hgb g/dL | 11.2 (9.4-12.6) | 11.4 (10.2-12.9) | 9.8 (8.9-12.2) | .20 |
| Platelets × 1000/μL | 176.5 (129-221) | 174 (138-221) | 186 (124-215) | .95 |
| Neutrophils count/μL | 3.8 (1.92-5.68) | 4.1 (2.02-5.42) | 3.64 (1.62-7.27) | .96 |
| Lymphocytes count/μL | 0.7 (0.34-1.09) | 0.7 (0.39-1.04) | 0.80 (0.14-1.26) | .83 |
| Neutrophil to lymphocyte ratio | 5.27 (2.89-9.46) | 5.14 (3.23-8.39) | 6.22 (1.97-14.17) | .70 |
| INR, median (IQR) | 1.1 (1-1.2) | 1.1 (1-1.2) | 1.2 (1.1-1.4) | .06 |
| Chemistries, median (IQR) | ||||
| Creatinine, mg/dLa | 1.89 (1.15-3.85) | 1.9 (1.15-3.47) | 1.9 (1.47-3.96) | .41 |
| Albumin g/dL | 3.6 (3.1-3.9) | 3.8 (3.2-4) | 3.35 (2.75-3.7) | .048 |
| AST U/L | 26 (17-36) | 24.5 (18-34) | 33 (17-48) | .39 |
| ALT U/L | 18 (13-25) | 18 (12-25) | 18 (14-24) | .51 |
| Total bilirubin mg/dL | 0.4 (0.3-0.5) | 0.4 (0.3-0.5) | 0.5 (0.4-0.6) | .04 |
| Additional labs, median (IQR)b | ||||
| HS-troponin ng/L | 27 (9-58.5) | 17.5 (8.5-43.5) | 52.5 (9.5-77) | .24 |
| Procalcitonin ng/mL | 0.285 (0.15-0.86) | 0.205 (0.12-0.7) | 0.73 (0.37-3.795) | .003 |
| CRP mg/L | 68.5 (15.445-126) | 60 (11-110) | 97 (18.6-130) | .20 |
| d-dimer μg/mL | 1.335 (0.69-3.08) | 1.04 (0.66-1.96) | 2.2 (0.99-3.81) | .13 |
| Ferritin ng/mL | 801.5 (270-1514) | 813 (257-1611) | 790 (466-1464) | .86 |
| IL-6 level pg/mL | 20 (8-51) | 18 (5-45) | 32 (11-90) | .26 |
a
Six patients were on chronic renal replacement therapy and not included in this calculation.
b
These values were not available for all patients (HS-troponin N = 44, procalcitonin N = 50, CRP N = 48, D-dimer N = 40, ferritin N = 46, IL-6 N = 33).