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. 2020 May 30;8(1):e000742. doi: 10.1136/jitc-2020-000742

Table 1.

Cytokines elevated in CRS

Cytokine Molecular weight (kDa)
Interleukin-6 (IL-6) 26 Proinflammatory
IL-10 18 Anti-inflammatory
Interferon-gamma 35 Proinflammatory
Tumor necrosis factor-α monomer 17 Proinflammatory
IL-1β 17 Proinflammatory
IL-2 17 Proinflammatory
IL-2 receptor Proinflammatory
IL-8, MCP-1, and MIP-1b IL-8–8 kDa Reported in patients treated with CART-19 and blinatumomab

CART, chimeric antigen receptor T cells; CRS, cytokine release syndrome.