Table 1.
Cytokines elevated in CRS
| Cytokine | Molecular weight (kDa) | |
| Interleukin-6 (IL-6) | 26 | Proinflammatory |
| IL-10 | 18 | Anti-inflammatory |
| Interferon-gamma | 35 | Proinflammatory |
| Tumor necrosis factor-α monomer | 17 | Proinflammatory |
| IL-1β | 17 | Proinflammatory |
| IL-2 | 17 | Proinflammatory |
| IL-2 receptor | Proinflammatory | |
| IL-8, MCP-1, and MIP-1b | IL-8–8 kDa | Reported in patients treated with CART-19 and blinatumomab |
CART, chimeric antigen receptor T cells; CRS, cytokine release syndrome.