Figure 6.
Typical simulated cell trajectories and (selected) cell morphologies for different values of ϕl and λF–actin. Each panel shows 10 cell trajectories of length 105 MCS, with Rcell = 15 (lattice sites)1/3. Axes show x and y positions measured relative to the center of the cell lattice in units of Rcell. The background color indicates confinement (cyan), persistent migration (gray), and artifactual lamellipodium detachment (light red). Larger λF–actin and smaller ϕl increase cell motility. When λF–actin is too small, the lamellipodium remains symmetrical and the cell does not migrate, whereas for very small ϕl, the lamellipodium is not strong enough to drive cell migration (data not shown). To see this figure in color, go online.