Figure 6.

Hydrodynamic properties of recombinant OAS1. (A) SV distribution analysis in terms of c(_S) at 0.5–3.5 g/L is shown. Inset is the resultant concentration dependence of the SV distribution. The values were corrected to standard conditions (pure water at 20°C). Error bars represent the width of the peak distribution. (B) Percent volume distribution profile is shown. OAS1 volume distribution by DLS in percent versus the hydrodynamic radius (r_H) at different protein concentrations (0.5–3.5 g/L) is shown. (C) Concentration dependence of the hydrodynamic radius was obtained from DLS measurements. The hydrodynamic radius (r_H) was determined for OAS1 by DLS at protein concentrations in the range as in (B). Error bars represent standard deviation from three replicates. To see this figure in color, go online.