Table 2.
Analyses of the relative and absolute changes in the primary and secondary outcomes for all subjects who completed the study.
| Within group comparison | ||||
|---|---|---|---|---|
| Low Load (N = 36) | High load (N = 33) | Difference between groups | P ANCOVA | |
| Primary outcome | ||||
| Relative change | ||||
| Body weight (%) | −0.31 (−0.70 to 0.08) | −1.68 (−2.09 to −1.27)*** | −1.37 (−1.96 to −0.79) | 1.5E-05 |
| Secondary outcomes | ||||
| Relative change | ||||
| Fat mass (%) | −0.79 (−2.46 to 0.88) | −4.82 (−6.57 to −3.08)*** | −4.04 (−6.53 to −1.55) | 1.9E-03 |
| Fat free mass (%) | −0.04 (−1.32 to 1.24) | 0.39 (−0.95 to 1.73) | 0.43 (−1.47 to 2.34) | 0.65 |
| Fat percent (%) | −0.48 (−2.17 to 1.20) | −3.18 (−4.95 to −1.42)*** | −2.70 (−5.21 to −0.19) | 0.035 |
| Absolute change | ||||
| Body weight (kg) | −0.30 (−0.66 to 0.05) | −1.61 (−1.98 to −1.24)*** | −1.31 (−1.84 to −0.78) | 6.3E-06 |
| Fat mass (kg) | −0.22 (−0.82 to 0.37) | −1.73 (−2.36 to −1.10)*** | −1.51 (−2.40 to −0.61) | 1.3E-03 |
| Fat free mass (kg) | −0.08 (−0.74 to 0.58) | 0.12 (−0.57 to 0.81) | 0.20 (−0.79 to 1.18) | 0.69 |
| Fat percent (%) | −0.16 (−0.83 to 0.51) | −1.25 (−1.95 to −0.54)*** | −1.09 (−2.09 to −0.08) | 0.034 |
The primary outcome was the relative change after 3 weeks in body weight. Results are presented as least square means with 95% confidence intervals for all randomized subjects with body weight available both at baseline and at 3 weeks treated with light weight vest (Low load; n = 36) or heavy weight vest (High load, n = 33). The between group p-values (High load vs Low load) given within the table are calculated using analysis of covariance (ANCOVA) adjusted for age, sex, baseline BMI, Vest exposure (h) and standing % with vest. *** = p<0.001 for within group comparison (Three weeks vs baseline) using Wilcoxon signed rank-sum test.