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. 2020 Apr 25;22:100293. doi: 10.1016/j.eclinm.2020.100293

Table 1.

Marginal type-specific risk of progression to CIN3+ of incident and prevalent single-type HPV infections, over 7 years of follow-up.

Length of infection HPV type1 Single-type HPV infections2
Frequency CIN3+ cases3
Cumulative risk of CIN3+ (%)
Total Detected at baseline Yr 0 Yr 1 Yr 3 Yr 5 Yr 7
Prevalent 16 1907 664 430 18.2 20.4 23.3 24.1 24.7
33 130 42 28 16.1 18.7 20.0 20.5 20.9
18 520 102 60 8.1 9.0 10.2 10.9 11.0
58 324 60 46 8.4 9.1 10.0 10.6 10.8
31 949 149 89 6.7 7.4 8.9 9.3 9.4
35 261 39 19 5.5 7.0 7.9 8.8 9.1
52 1073 130 73 4.6 5.2 6.5 6.7 6.9
45 371 50 35 5.3 5.7 6.3 6.7 6.8
39 268 20 13 2.7 3.2 3.8 3.9 3.9
56 253 14 11 2.2 2.2 2.4 2.6 2.7
51 603 30 15 1.6 1.9 2.5 2.6 2.6
68 174 7 3 0.8 1.3 1.9 2.1 2.1
59 189 8 4 1.3 1.6 1.9 2.0 2.0
Prevalent Total 7022 1315 826 (62.8%)
Incident 16 472 87 42 6.2 7.8 9.6 10.8 10.9
33 44 8 5 7.6 9.2 11.0 11.1 11.1
18 176 27 16 5.6 6.2 7.1 7.8 7.9
58 91 6 6 3.3 3.3 3.3 3.3 3.3
31 299 21 10 2.4 2.6 3.0 3.4 3.5
35 71 5 4 3.8 3.8 3.8 3.8 3.8
52 321 15 8 1.6 1.7 2.2 2.4 2.4
45 143 11 5 2.2 2.4 3.1 3.8 4.0
39 85 5 3 2.1 2.5 2.8 2.8 2.8
56 103 3 0 0.0 0.7 0.9 0.9 1.2
51 287 10 3 0.7 0.9 1.4 1.6 1.7
68 55 4 3 3.4 3.4 3.4 3.4 3.4
59 66 2 0 0.0 0.1 0.8 1.6 1.8
Incident Total 2213 204 105 (51.5%)
All infections Total 9235 1519 931 (61.2%)
1

Ordered based on descending risk of CIN3+ for prevalent (most common) single type infections.

2

Risk estimates restricted to single-type HPV infections.

3

Average time to end of follow-up was 4.1 years for prevalent infections and 4.9 years for incident ones.