Table 3.
The differences in volumes of the brainstem subregions between normal controls and MDD patients
| Regions | Normal controls | MDD | F | p | FDR p |
|---|---|---|---|---|---|
| Medulla | 4,197.9±397.36 | 4.134.6±297.05 | 0.683 | 0.414 | ns |
| Pons | 13,143.4±1,530.58 | 12,983,4±1,305.66 | 0.341 | 0.563 | ns |
| SCP | 221.2±42.58 | 237.6±36.37 | 1.724 | 0.197 | ns |
| Midbrain | 5,440.6±444.35 | 5,337.5±380.15 | 2.294 | 0.138 | ns |
| Whole brainstem | 23,003.0±2,266.93 | 22,693.1±1,844.46 | 0.652 | 0.425 | ns |
The volumetric group differences in subcortical nuclei were tested using analysis of covariance with age, duration of education, and TICV as covariates. The data are expressed as mean±standard deviation (mm3). MDD: major depressive disorder, FDR: false discovery rate by Benjamini and Hochberg, ns: not significant, SCP: supracerebellar peduncle