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. 2020 Jun 1;6(6):e04082. doi: 10.1016/j.heliyon.2020.e04082

Table 2.

Experimental protocol.

Group A: Saline Mice were intraperitoneally (i.p.) injected with saline once per week over a period of 12 weeks. Saline is the vehicle used to dissolve DMH.
Group B: Extract Mice received M. chamomilla aqueous extract only at 150 mg/Kg/ b.w. by gavage (P.O.) 5 days/week for 12 weeks.
Group C: DMH 12 weeks Mice received DMH dissolved in saline (20 mg/Kg b.w., i.p.) once per week over 12 weeks to induce colorectal cancer (CRC).
Group D: Pre-treatment Mice were pre-treated with M. chamomilla extract (150 mg/Kg/ b.w.) starting 1 week before DMH injections and continued till 1 week after the final DMH exposure.
Group E: DMH 24 weeks Mice received DMH for 12 weeks as in group C and left without any treatment for an additional 12 weeks.
Group F: Post-treatment Mice received M. chamomilla extract (150 mg/Kg/ b.w.) starting 1 week after the twelfth DMH injection and continued over additional 12 weeks.