Table 1.
Timeline of the measurements to be taken at each point on the trials
| Timeline | Enrolment | STE protocol training | Baseline assessment (A1) |
Intervention | Postintervention assessment (A2) |
Follow-up assessment (A3) |
Follow-up assessment (A4) |
| −2 weeks (–14 to −7 days) |
−1 week (–7 to 0 day) |
Day 0 | 8 weeks (±3 days) |
20 weeks (±3 days) |
32 weeks (±3 days) |
||
| Enrolment | |||||||
| Eligibility screen | X | ||||||
| Informed consent | X | ||||||
| Interventions | |||||||
| Allocation | X | ||||||
| STE | X | ||||||
| STE+cryotherapy | X | ||||||
| STE+sham cryotherapy | X | ||||||
| X-ray examination of both knees | X | ||||||
| Assessments | |||||||
| VAS | X | X | X | X | |||
| WOMAC | X | X | X | X | |||
| SF-36 | X | X | X | X | |||
| Timed-up and Go Test | X | X | X | X | |||
| 30 s chair to stand test | X | X | X | X | |||
| Stair climb test | X | X | X | X | |||
| 40 m (4×10 m) fast paced walk test | X | X | X | X | |||
A, assessment; KOOS, Knee Injury and Osteoarthritis Outcome Score; SF-36, Short Form-36 questionnaire.STE, Strength therapeutic exercises; VAS, Visual Analogue Scale, WOMAC: Western Ontario & McMaster Universities Osteoarthritis questionnaire.