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. 2020 Jun 1;8:76. doi: 10.1186/s40168-020-00836-7

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Relative abundance distribution of the most abundant functional categories in TMM-normalized metagenome sequencing data from the shotgun metagenome of cultivated microorganisms. a COG annotation (10 most abundant ). b KEGG annotation (10 most abundant). c dbCAN annotation (10 most abundant). The descriptions of the functions displayed in b and c are detailed in Supplementary Table S4. Average from 2 replicates per plate of culture medium. E-amino acid transport and metabolism; G-carbohydrate transport and metabolism; H-coenzyme transport and metabolism; C-energy production and conversion; I-lipid transport and metabolism; F-nucleotide transport and metabolism; Q-secondary metabolites; D-cell cycle; N-cell motility; M-cell wall/membrane/envelope biogenesis; V-defense mechanisms; P-inorganic ion transport and metabolism; U-intracellular trafficking; O-post translational modification; T-signal transduction mechanisms; L-replication, recombination, and repair; K-transcription; J-translation; S-function unknown; R-general function and prediction; X-mobilome