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. 2020 Jun 2;11(6):416. doi: 10.1038/s41419-020-2517-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Representative images of HE staining of pancreatic tissues from the indicated groups. b Quantitative analysis of injured areas in the indicated groups. Serum lipase (c) and amylase (d) levels were detected by ELISA. e Western blot analyses were used to show the levels of DC-SIGN, P-mTOR and total mTOR. f Immunohistochemical images were used to visualize the distribution of DC-SIGN in the indicated groups. The red arrows indicate DC-SIGN-positive acini. Quantitative analysis of DC-SIGN-positive areas in the indicated groups. n = 6 mice per group. The data are presented as the means ± SEs. *P < 0.05, **P < 0.01 vs. the sham group. AP, acute pancreatitis; P-mTOR, phosphorylated mTOR.