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Mitotic entry of parental RPE cyclin B1-Venus+/−:MAD2-Ruby+/− cell. Cyclin B1-Venus (left panel), Ruby-MAD2 (middle panel), and merged channels cyclin B1-Venus (green) and Ruby-MAD2 (red; right panel). Cells imaged by spinning disk confocal microscopy. Frame rate, one image every 2 min.
