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. 2020 Jun 2;10:8942. doi: 10.1038/s41598-020-65645-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cone metrics were analyzed as a function of axial length at eccentricities of 0.2 mm (blue squares), 0.3 mm (orange circles), and 0.5 mm (gray triangles) for 29 subjects. Lines show linear regressions for those data that possessed a statistically significant relationship. (A) Linear cone density (cones/mm²) significantly decreased with increasing axial length only at an eccentricity of 0.2 mm (linear cone density [x 1,000 cones/mm²] = −5.2913 × (axial length, in mm) +180.08, P = 0.001). (B) Angular cone density (cones/deg²) was not significantly related to axial length at any examined eccentricity. (C) Farthest neighbor distance significantly increased in eyes with longer axial lengths only at an eccentricity of 0.2 mm (farthest neighbor distance = 0.312 × (axial length, in mm) − 1.2785, P = 0.002).