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. 2020 Jun 2;10:8942. doi: 10.1038/s41598-020-65645-2

Table 3.

Comparison of linear cone density measurements between previously published ex vivo and in vivo studies with measurements from the current study.

Study Ex Vivo In Vivo Adult In Vivo Children/Adult In Vivo Children
Curcio et al.25 Li et al.26 Song et al.30 Elsner et al.27 Lombardo et al.23 Park et al.15 Current work
Number of subjects 7 18 10 36 12 36 29
Age range (years) 27–44 23–44 22–35 18–34 24–38 10–20 5–16
Axial length range (mm) Not reported 22.9–28.3 22.1–26.1 23.2–25.8 22.6–26.6 22.01–28.43 20.86–25.64
Linear Cone Density (cones/mm2) at eccentricities of:
~0.20 mm 73,000 78,900 ± 9300 67,400 ± 15,600 (0.18 mm) Not reported Not reported Not reported 55,897 ± 6,698
~0.30 mm 53,500 57,000 ± 6800 56,700 ± 7,900 (0.27 mm) 43,216 ± 6,039 (0.27 mm) 49,393 ± 7,941 (0.26 mm) Not reported 47,009 ± 4,802
~0.40 mm 42,200 Not reported 46,800 ± 8,300 (0.36 mm) Not reported 38,000 Not reported Not reported
≥0.50 mm 36,000 (0.50 mm) Not reported 38,800 ± 7,500 (0.45 mm) 27,466 ± 3,496 (0.63 mm) 30,049 ± 4,954 (0.6 mm) 32,554 ± 2,884 (0.50 mm) 32,556 ± 3,954 (0.50 mm)
Meridians reported All All All All Horizontal All All