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. 2020 Jun 2;11(6):412. doi: 10.1038/s41419-020-2617-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — a Representative images (scale bars, 500 and 50 μm) of ISH or IHC staining for RUNX1-IT1, RUNX1, C-FOS, MMP9 and CCND1 in tissues from different clinical stages (I–IV) are shown. b–e Bar charts showing the correlation between the expression of RUNX1-IT1 and RUNX1, C-FOS, MMP9 and CCND1. f General correlation analysis of RUNX1-IT1, RUNX1, C-FOS, MMP9 and CCND1. (*P < 0.05, **P < 0.01, ***P < 0.001).