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. 2020 Jun 2;10:9018. doi: 10.1038/s41598-020-65528-6

Table 2.

Analysis of association between FMD and some relevant parameters by univariate and multivariate linear regression in baseline.

Univariate Rho (p) Multivariate Beta (p)
Baseline data (r2 = 0.74)
ADMA (µmol/l) −0.78 (<0.001) −0.38 (<0.001)
Malondialdehyde (MDA) (nmol/ml) −0.68 (<0.001) NS
CuZn-SOD (U/ml) 0.66 (<0.001) 0.13 (0.01)
GSH-Px (U/ml) 0.32 (<0.001) NS
PTX3 (ng/ml) −0.61 (<0.001) −0.14 (0.01)
hs-CRP (mg/l) −0.72 (0.02) NS
eGFR (ml/min/ 1.73 m2) 0.23 (0.001) NS
Hemoglobin (g/dl) 0.59 (<0.001) 0.33 (<0.001)
Total Cholesterol (mg/dl) −0.51 (<0.001) NS
Triglyceride (mg/dl) −0.17 (<0.001) NS
LDL cholesterol (mg/dl) −0.27 (<0.001) NS
HDL cholesterol (mg/dl) 0.13 (0.05) NS
Systolic blood pressure (mmHg) −0.59 (<0.001) −0.13 (0.004)
Diastolic blood pressure (mmHg) −0.27 (<0.001) NS
Serum albumin (g/dl) 0.08 (0.23) NS
HOMA-IR −0.29 (<0.001) NS
HbA1c (%) −0.54 (<0.001) NS

ADMA: Asymmetric dimethyl arginine; HOMA, homeostasis model assessment; eGFR, estimated glomerular filtration rate; hsCRP, high sensitivity C reactive protein; PTX3, pentraxin 3; CuZn-SOD, copper zinc-superoxide dismutase; GSH-Px, glutathione peroxidase; MDA, Malondialdehyde.