Table 3.
Analysis of association between FMD and some relevant parameters by univariate and multivariate linear regression after 12 weeks of AAL, AIC and AOL therapies.
| Univariate Rho (p) | Multivariate Beta (p) | |
|---|---|---|
| Baseline data (r2 = 0.63) | ||
| ADMA (µmol/l) | −0.68 (<0.001) | −0.35 (<0.001) |
| Malondialdehyde (MDA) (nmol/ml) | −0.69 (<0.001) | −0.30 (<0.001) |
| CuZn-SOD (U/ml) | 0.42 (<0.001) | NS |
| GSH-Px (U/ml) | 0.11 (0.09) | NS |
| PTX3 (ng/ml) | −0.34 (<0.001) | −0.12 (0.007) |
| hs-CRP (mg/l) | −0.38 (<0.001) | −0.21 (<0.001) |
| eGFR (ml/min/ 1.73 m2) | 0.35 (<0.001) | 0.14 (0.002) |
| Hemoglobin (g/dl) | 0.12 (0.06) | NS |
| Total Cholesterol (mg/dl) | −0.11 (0.09) | NS |
| Triglyceride (mg/dl) | −0.38 (<0.001) | NS |
| LDL cholesterol (mg/dl) | −0.26 (<0.001) | NS |
| HDL cholesterol (mg/dl) | 0.09 (0.25) | NS |
| Systolic blood pressure (mmHg) | −0.15 (0.04) | NS |
| Diastolic blood pressure (mmHg) | −0.20 (0.004) | −0.12 (0.004) |
| Serum albumin (g/dl) | 0.09 (0.20) | NS |
| HOMA-IR | −0.32 (<0.001) | NS |
ADMA: Asymmetric dimethyl arginine; HOMA, homeostasis model assessment; eGFR, estimated glomerular filtration rate; hsCRP, high sensitivity C reactive protein; PTX3, pentraxin 3; CuZn-SOD, copper zinc-superoxide dismutase; GSH-Px, glutathione peroxidase; MDA, Malondialdehyde.