Table 4.
Analysis of association between change (∆) in FMD and relevant parameters by univariate and multivariate linear regression analysis.
| Univariate Rho (p) | Multivariate Beta (p) | |
|---|---|---|
| ∆ FMD (%) (r2 = 0.30) | ||
| Change in ADMA (µmol/l) | −0.63 (<0.001) | −0.25 (0.01) |
| Change in MDA (nmol/ml) | −0.58 (<0.001) | −0.18 (0.02) |
| Change in CuZn-SOD (U/ml) | 0.48 (<0.001) | NS |
| Change in GSH (U/ml) | 0.02 (0.75) | NS |
| Change in HOMA | −0.21 (0.001) | NS |
| Change in eGFR (ml/min/ 1.73 m2) | −0.03 (0.62) | NS |
| Change in hsCRP (mg/l) | −0.45 (<0.001) | NS |
| Change in PTX3 (ng/ml) | −0.49 (<0.001) | −0.21 (0.01) |
| Change in SBP (mmHg) | −0.26 (<0.001) | NS |
| Change in DBP (mmHg) | −0.11 (0.12) | NS |
| Change in Hemoglobin (g/dl) | 0.07 (0.32) | NS |
| Change in Total Cholesterol (mg/dl) | −0.05 (0.49) | NS |
| Change in Triglyceride (mg/dl) | −0.11 (0.12) | NS |
| Change in LDL Cholesterol (mg/dl) | −0.12 (0.07) | NS |
| Change in HDL Cholesterol (mg/dl) | 0.02 (0.82) | NS |
| Change in HbA1c (%) | −0.26 (<0.001) | NS |
ADMA: Asymmetric dimethyl arginine; HOMA, homeostasis model assessment; eGFR, estimated glomerular filtration rate; hsCRP, high sensitivity C reactive protein; PTX3, pentraxin 3; CuZn-SOD, copper zinc-superoxide dismutase; GSH-Px, glutathione peroxidase; MDA, Malondialdehyde.