Table 3.

Multivariate hazard ratio (95% confidence interval) for biochemical relapse after prostatectomy for established risk factors and YAP1 expression in the preoperative model.

Variable	Category	Cytoplasmic	Nuclear
		n = 5,290	n = 8,553
Gleason grade biopsy	≥4 + 4 vs. ≤3 + 3	4.1 (3.6–4.7) ***	4.2 (3.7–4.7) ***
Preoperative PSA level	≥20 vs. <4	3.2 (2.7–3.9) ***	3.2 (2.7–3.9) ***
cT stage	T2c vs. T1c	2.2 (1.8–2.8) ***	2.1 (1.7–2.6) ***
YAP1 expression	Strong vs. negative	1.6 (1.3–1.9) ***	1.3 (1.1–1.5) **

Categories with the highest hazard ratio are shown for each variable ranked in decreasing order; *p ≤ 0.05, **p ≤ 0.001, ***p ≤ 0.0001