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Biosynthetic pathways of the principal cannabinoids in the Cannabis plant. CBGA is formed by conjugation of geranyl pyrophosphate to olivetolic acid under the influence of enzyme [I] GOT.10 CBGA is then the precursor for CBCA, CBDA and THCA formed by enzymes [II] CBCA synthase,13 [III] CBDA synthase14 and [IV] THCA synthase.15
