Figure 3.

Correlation of treatment response with % change in LGI. (A) TR was significantly correlated, negatively, with % change in LGI in the inferior parietal cortex bilaterally, the left middle frontal cortex, and precentral gyrus, and the right inferior frontal cortex, and cuneus (P < .05). Models were corrected for age and eTIV. Multiple comparisons corrected for with Monte Carlo null-z simulations (P < 0.05). Individual averages for (B) % change in LGI were extracted from a hand-traced middle frontal ROI and plotted with TR. eTIV = estimated total intracranial; LGI = local gyrification index; SZ = patients with schizophrenia; TR = treatment response; ROI = region of interest; L = left; R = right.